Improved cerebral autoregulation in patients with parkinsons disease and autonomic failure
C Haubrich, K Pies, M Dafotakis, R Diehl, C Klötzsch, F Block · Klinische Neurophysiologie · 2006 · Heft 03
Bibliografische Angaben
Zusammenfassung
Background: Parkinsons disease (PD) is considered as a combination of a movement disorder and dysautonomia. Whereas cardiovascular autonomic dysfunctions have been studied intensively little is known about the regulation of cerebral blood flow in PD. This study examined cerebral autoregulatory dynamics in patients with orthostatic hypotension (OH). Methods: 18 patients with long standing idiopathic parkinsons disease (PD) and tilt-induced OH were examined with Transcranial Doppler of the PCA and MCA as well as beat-to-beat systemic blood pressure in supine and 80° tilted positions. Cerebral blood flow velocity (…