Is peginterferon-alpha plus ribavirin therapy safe and effective for patients with chronic hepatitis C and ulcerative colitis? – a case report
E Schäfer, T Gyökeres, C Mikes, A Bursics, Á Pap · Zeitschrift für Gastroenterologie · 2006 · Heft 06
Bibliografische Angaben
Zusammenfassung
Introduction: We report on a 55-year old man with chronic hepatitis C, who showed exacerbation of ulcerative colitis during peginterferon-alpha and ribavirin therapy. Case: At the initiation of antiviral therapy, ulcerative colitis was in complete remission with 5-ASA monotherapy. In response to the treatment at week 12, HCV-PCR became negative and ALT and AST levels returned to the normal limit, ulcerative colitis showed neither clinical, nor laboratory activity. Continuation of this well tolerated therapy was planned until week 48 because of genotype I of HCV infection. At week 46, the patient was admitted to…