Computer-assisted colonoscopy (the NeoGuide system): Results of the first human clinical trial (PACE Study)

Aims: Unsedated colonoscopy is an uncomfortable procedure for most patients. The majority of procedures in most centers are performed using moderate sedation with an anxiolytic medication, narcotic analgesia, a combination of both, or deep sedation (e.g., propofol). Discomfort during colonoscopy is largely related to looping of the colonoscope, which displaces the colon from its native configuration and stretches attachments to the mesentery. A novel computer-assisted colonoscope (NeoGuide Systems, Inc., Los Gatos, CA) utilizes a fully articulated, computer-controlled insertion tube. On manual insertion of the c…