CareLit Fachartikel
Neoadjuvant chemotherapy in patients with advanced ovarian cancer: preoperative response evaluation – Results from a prospective mutlicenter phase II study
M Pölcher, S Mahner, O Ortmann, J Hilfrich, M Braun, W Kuhn · Geburtshilfe und Frauenheilkunde · 2008 · Heft 09
Dokument
1103810
CareLit-ID
Jahr
2008
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben
Zusammenfassung
Purpose To evaluate the response to neoadjuvant chemotherapy (NAC) in patients with epithelial ovarian cancer (EOC). Patients and Methods Patients with FIGO stage IIIC or IV EOC and an ascites volume of ≥ 500ml were randomly assigned to receive three (A1) or two (A2) of six cycles of carboplatin and docetaxel IV preoperatively. Baseline serum CA 125 levels were measured, and computed tomography (CT) scans and vaginal ultrasounds were performed to determine target lesions and the volume of ascites. This was repeated after two, or two and three courses of NAC respectively. The primary outcome measure was the preop…
Schlagworte
CA 125
CT
ascites
chemotherapy
ovarian cancer
After
Carboplatin
Tumor
Geburtshilfe und Frauenheilkunde
