CareLit Fachartikel
Success treatment of adult primary vulvar Langerhans cell histiocytosis with thalidomide
FS Suwandinata, F Franke, HR Tinneberg, K Münstedt · Geburtshilfe und Frauenheilkunde · 2008 · Heft 09
Dokument
1103831
CareLit-ID
Jahr
2008
Publikation
PDF
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Metadaten
DOI
ja
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Bibliografische Angaben
Zusammenfassung
Due to rarity of primary vulvar Langerhans cell histiocytosis (LCH) and lack of randomized clinical trials, treatment of genital LCH is still non-standardized. We describe a case in which the LCH was confined to the vulva, with review of the literature. The review showed different response and recurrence rate of each therapy modality. First line treatment of isolated vulvar LCH included surgery, radiotherapy, chemotherapy and topical therapy. Overall outcome was good but the risk of recurrence was high (up to 42%–50%). Mean time to relapse was 18.3±12.4 months. In our case, a 59-year-old woman presented with pru…
Schlagworte
vulvar Langerhans cell histiocytosis
vulvar malignancy
vulvar ulcers
After
Biopsy
Work
Geburtshilfe und Frauenheilkunde
