Cerebral metastases (CM) in breast cancer (BC) with focus on “triple- negative“ (TN) tumors
F Heitz, P Harter, B Beutel, HJ Lueck, A Traut, A du Bois · Geburtshilfe und Frauenheilkunde · 2008 · Heft 09
Bibliografische Angaben
Zusammenfassung
Purpose: We analysed the impact of TN-BC -characterized by ER-/PR-/Her2neu- in respect of CM Methods: Retrospective analysis of in 3,193 BC pts. treated consecutively between '89 and '06 in our EUSOMA breast unit. All pts. developing CM were included. Results: 338 pts. suffered from TN-BC (10.58%) and 80 pts. (2.5%) developed CM within a median observation period of 51 months. 19 pts. (23.75%) with CM had TN-BC and 5,6% with TN-BC had CM. Multivariate analysis indicated the highest risk for developing CM for TN-BC compared with all other types of BC (OR: 4.16; 95% CI: 2.26–7.64;p