Affective Disturbances Modulate the Neural Processing of Visceral Pain Stimuli in Irritable Bowel Syndrome: An fMRI Study
S Elsenbruch, C Rosenberger, M Schedlowski, M Forsting, ER Gizewski · Psychotherapie Psychosomatik Medizinische Psychologie · 2009 · Heft 02
Bibliografische Angaben
Zusammenfassung
Aim and methods: In N=15 female irritable bowel syndrome (IBS) patients and N=11 healthy women, we assessed the correlation of trait anxiety and depression, respectively, with the neural response to painful rectal distensions in women with irritable bowel syndrome (IBS) and healthy women. Trait anxiety and depression were assessed with the Hospital Anxiety and Depression Scale (HADS). Results: I.) Multiple regression analyses within the IBS group revealed that anxiety scores were significantly associated with pain-induced activation of the insular cortex (IC) and the anterior cingulate cortex (ACC). Depression s…
