Functional connectivity in patients with early Alzheimers disease, MCI and healthy controls assessed by fMRI and EEG
D Keeser, S Teipel, T Meindl, A Medvedeva, S Karch, G Leicht, HJ Möller, M Reiser, C Mulert, O Pogarell · Klinische Neurophysiologie · 2009 · Heft 03
Bibliografische Angaben
Zusammenfassung
Alzheimer's disease (AD) is a neurodegenerative disorder selectively involving cerebral neuronal networks facilitating higher cognitive functions. Coherence measured by electroencephalography (EEG) is a sensitive marker for functional connectivity in the brain, whereas functional magnetic resonance imaging (fMRI) allows the detection of activation patterns. The aim of this study was to correlate fMRI activation patterns and EEG-coherence in patients with AD, mild cognitive impairment (MCI) and age-matched healthy controls (HC). The aim of this study was to correlate fMRI activation patterns and EEG-coherence in…