Inhibition of movement representation by transcranial magnetic stimulation timed to event-related synchronization

Practice-induced motor memory may be enhanced if TMS is applied to the primary motor cortex (M1) synchronously with movement performance. However, synchronous TMS will facilitate movement memory formation indiscriminately of their similarity to the desired goal. Event-related synchronisation (ERS), an oscillatory EEG phenomenon after termination of a movement may reflect a deactivated cortical state or local cortical inhibition. We tested the hypothesis that post-movement TMS synchronized with ERS is able to disfacilitate training-induced changes in movement representation. 10 healthy volunteers participated in…