Early Experiences with Radiofrequency Ablation of Barrett's Esophagus

Background: Barrett's esophagus (BE) is associated with an increased risk for developing dysplasia and adenocarcinoma. Current endoscopic treatment consists of endoscopic mucosal resection (EMR) for patients with high grade intraepithelial neoplasia (HGIN) and adjacent areas of BE. Thermal destruction by means of radiofrequency ablation is a promising new technique for the treatment of BE without major complications like perforation or stenosis reported so far. The aim of the study was to assess the efficacy and safety of stepwise circumferential and focal ablation of BE using the HALO® system. Methods: Patients…