CareLit Fachartikel

Influence of insulin resistance on adiponectin receptor expression in breast cancer

G Pfeiler, G Wenzl, A Hartmann, G Schmitz, O Treeck, O Ortmann · Geburtshilfe und Frauenheilkunde · 2009 · Heft 06

Dokument
1105046
CareLit-ID
Jahr
2009
Publikation
PDF
nein
Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Geburtshilfe und Frauenheilkunde
Autor:innen
G Pfeiler, G Wenzl, A Hartmann, G Schmitz, O Treeck, O Ortmann
Ausgabe
Heft 06 / 2009
Seiten
–
Erschienen: 2009-06-17 00:00:00
ISSN
0016-5751
DOI
10.1055/s-0029-1225217

Zusammenfassung

Objective: Adipostas and insulin resistance are modifiable risk factors for breast cancer. Adiponectin seems to be an important linkage of these associations. In this study we investigated the relationship between insulin resistance and intratumoral adiponectin receptor expression and analysed the relationship between insulin/IGF receptor and adiponectin receptor expression in breast cancer specimen. Methods: Breast cancer tissue and fasting serum were collected from 26 female patients. After microdissection of frozen samples, RNA was isolated and expression of insulin receptor, IGFR1, IGFR2, AdipoR1 and AdipoR2…

Schlagworte

Breast Adiponectin C-Peptide After Geburtshilfe und Frauenheilkunde