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Development of inclusion bodies late in the course of necrotizing myositis due to systemic lupus erythematosus

P Zickler, E Neuen-Jacob, S Jander · Aktuelle Neurologie · 2009 · Heft 10

Dokument
1105227
CareLit-ID
Jahr
2009
Publikation
PDF
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Metadaten
DOI
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Zeitschrift
Aktuelle Neurologie
Autor:innen
P Zickler, E Neuen-Jacob, S Jander
Ausgabe
Heft 10 / 2009
Seiten
–
Erschienen: 2009-10-07 00:00:00
ISSN
0302-4350

Zusammenfassung

Background: The diagnosis of myositis and its nosological differentiation into polymyositis, inclusion body myositis (IBM) and myositis associated to systemic autoimmune diseases strongly relies on muscle biopsy findings. We report a case of necrotizing polymyositis associated to systemic lupus erythematosus (SLE) which 11 years later developed inclusion bodies and other histopathological features typical for IBM. Case report: A 45-year-old man presented in 1997 with progressive proximal symmetric tetraparesis pronounced for the upper extremities (grade 4/5) and discoid skin lesions. Further investigations were…

Schlagworte

Biopsy Diagnosis Azathioprine After Autoimmune Diseases Creatine Kinase Creatine Aktuelle Neurologie