Development of inclusion bodies late in the course of necrotizing myositis due to systemic lupus erythematosus
P Zickler, E Neuen-Jacob, S Jander · Aktuelle Neurologie · 2009 · Heft 10
Bibliografische Angaben
Zusammenfassung
Background: The diagnosis of myositis and its nosological differentiation into polymyositis, inclusion body myositis (IBM) and myositis associated to systemic autoimmune diseases strongly relies on muscle biopsy findings. We report a case of necrotizing polymyositis associated to systemic lupus erythematosus (SLE) which 11 years later developed inclusion bodies and other histopathological features typical for IBM. Case report: A 45-year-old man presented in 1997 with progressive proximal symmetric tetraparesis pronounced for the upper extremities (grade 4/5) and discoid skin lesions. Further investigations were…