Modulation of gait coordination by subthalamic stimulation improves freezing of gait
J Herzog, A Fasano, R Reese, J Volkmann, G Deuschl · Aktuelle Neurologie · 2009 · Heft 10
Bibliografische Angaben
Zusammenfassung
Objective: To study how modulation of symmetry between both legs by subthalamic deep brain stimulation (STN-DBS) impacts on freezing of gait (FOG) in patients with Parkinson's disease (PD). Methods: 22 PD patients (13 FOG+) with STN-DBS for at least six months were evaluated in the following four conditions: STN-DBS on (ON) and off (OFF), 50% reduction of stimulation voltage for the leg with shorter stride (worse side reduction, WSR) and longer stride (better side reduction, BSR). Gait analysis was performed on a treadmill and recorded by an opto-electronic analysis system. We measured frequency and duration of…