Quantitative HPTLC determination of stachydrine in cardioactive plant drugs such as in an antiarrhythmic refined extract of Leonurus cardiaca Ph.Eur
K Kuchta, RB Volk, HW Rauwald · Zeitschrift für Phytotherapie · 2009 · Heft 08
Bibliografische Angaben
Zusammenfassung
Antiarrhythmic drugs of chemical origin are in clinical use since decades but their application is often limited by adverse effects and especially by an inherited proarrhythmic risk [1]. In contrast, tea preparations from aerial parts of the European plant Leonurus cardiaca L. are traditionally used as a remedy against tachyarrhythmia, heart failure, and other cardiac disorders [2–4]. Nevertheless, a scientific basis for these therapeutic effects has not been established up to now [5]. Recently, an antiarrhythmic refined extract was prepared from L. cardiaca via bioassay guided fractionation [6], making the deve…