Evaluation of serum cytokeratin-18 as prognostic parameter for acute liver failure
LP Bechmann, M Kaßalik, C Jochum, RK Gieseler, G Marquitan, F Saner, A Paul, G Gerken, A Canbay · Zeitschrift für Gastroenterologie · 2009 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background and aims: Acute liver failure (ALF) is a devastating clinical syndrome associated with a high mortality rate. In many cases, the etiology remains unknown and despite clinical criteria, it is challenging to pinpoint individuals with ALF that are able to survive without liver transplantation (LTx). The aim of the study was to determine whether cell death markers have the potential to predict the clinical course of ALF and/or may be utilized to differentiate etiologies. Methods: In a prospective monocenter study (11/2006–09/2008), we recruited 52 consecutive ALF patients (56% females/44% males), who met…
