Radiation-induced acute phase reaction: correlation between radiation-induced proctitis and increased hepcidin serum levels
H Christiansen, B Saile, RM Hermann, M Rave-Fränk, A Hille, H Schmidberger, CF Hess, G Ramadori · Zeitschrift für Gastroenterologie · 2007 · Heft 01
Bibliografische Angaben
Zusammenfassung
Purpose To analyse hepcidin serum and urine levels during radiotherapy for prostate cancer. Methods In 18 patients undergoing radiotherapy for prostate cancer, blood, plasma, and urine samples were taken before and during radiotherapy. Complete blood cell count, pro-hepcidin-, ferritin-, transferrin-, IL–1β-, IL–6-, and TNF-α concentration was determined. Pro-hepcidin concentration was additionally measured in urine samples. Toxicity was evaluated weekly. Differences among tested factors were tested by Wilcoxon Rank Sign Test for paired data. Results In 10 patients developing acute radiation-induced proctitis, a…
