Correlation of histologic results with PET findings for tumor regression and survival in locally advanced non-small cell lung cancer after neoadjuvant treatment
M Schmuecking, RP Baum, TG Wendt, CP Schneider, N Presselt, R Bonnet, C Marx, K Junker, KM Mueller · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2007 · Heft 05
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Zusammenfassung
Ziele: CT cannot provide useful information in a timely manner after neoadjuvant treatment. To evaluate the role of (18)F FDG PET after neoadjuvant chemoradiation for early therapy response and its effect on survival as compared to histopathologic tumor response, findings in 32 patients were analyzed prospectively in an ongoing multicenter trial (LUCAS-MD). Methode: Inclusion criteria: histologically confirmed NSCLC stage IIIA/IIIB. Neoadjuvant treatment: 2–3 cycles with paclitaxel/carboplatin and a block of chemoradiation followed by surgery. Pretherapeutic staging: F-18 FDG PET scan in addition to a spiral CT…