Predictors of outcome in PEG-IFN+RBV treated HCV1 patients in Hungary. The role of rapid virological response

Aim: We assessed the predictors of response to PEG-IFN+RBV treatment for HCV1 patients in a nation-wide retrospective study and in a prospective trial. Patients and methods: In the first analysis, 2442 (1330 males, 1112 females) patients, while in the second trial 69 (51 males, 18 females), patients have been investigated. The following parameters were studied: age, gender, BMI, adherence, pretreatment viral load, rapid (RVR) and early virological response (EVR), all in relation to the sustained virological response (SVR). Results: In the nation-wide study the SVR rate was 31%, while in the prospective trial it…