Evaluation of the intraoesophageal pH patterns in patients with bronchial hyperreactivity (BHR)

Aims: Gastroesophageal reflux (GER) is considered a significant pathogenetical factor in the development of BHR. The aim of the study was to evaluate the intraoesophageal pH patterns in patients with BHR. Patients and methods: 43 consecutive patients (M/F 12/31) with recent diagnosis of BHR were prospectively studied. 20 patients with chronic cough, but without BHR were evaluated as controls. Patients were all submitted to reflux symptom analysis, upper gastrointestinal endoscopy, oesophageal manometry, and Bernstein-test. Proximal GER reflux was established by double channel intraoesophageal pH monitoring. The…