Neuropsychological and psychiatric sequelae of deep-brain stimulation for Parkinson's disease – a randomized, controlled, multicenter study
C Daniels, K Witt, J Reiff, P Krack, M Krause, K Boetzel, A Schnitzler, L Wojtecki, R Hilker, E Kalbe, GH Schneider, A Kupsch, G Deuschl · Aktuelle Neurologie · 2007 · Heft 09
Bibliografische Angaben
Zusammenfassung
Objective: To evaluate the neuropsychological and psychiatric effects of bilateral deep brain stimulation of the subthalamic nucleus (STN-DBS) compared to optimized medical treatment in advanced Parkinson s disease (PD) in a randomized controlled study. Background: STN-DBS markedly reduces parkinsonian symptoms in patients with advanced Parkinson s disease and leads to a significant improvement of quality of life. Two controlled studies on the neuropsychological effects of STN-DBS reported a mild deterioration of attention and executive functioning, but in both studies no randomization between surgery and best m…
