CareLit Fachartikel
Evidence for a wide extra-astrocytic distribution of S100B in human brain
J Steiner, HG Bernstein, H Bielau, C Mawrin, G Keilhoff, B Bogerts · Aktuelle Neurologie · 2007 · Heft 09
Dokument
1106498
CareLit-ID
Jahr
2007
Publikation
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Metadaten
DOI
ja
zitierfähig
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Zusammenfassung
Background: S100B is considered an astrocytic in-situ marker and protein levels in cerebrospinal fluid (CSF) or serum are often used as biomarker for astrocytic damage or dysfunction. However, studies on S100B in the human brain are rare. Thus, the distribution of S100B was studied by immunohistochemistry in adult human brains to evaluate its cell-type specificity. Results: Contrary to glial fibrillary acidic protein (GFAP), which selectively labels astrocytes and shows only faint ependymal immunopositivity, a less uniform staining pattern was seen in the case of S100B. Cells with astrocytic morphology were prim…
Schlagworte
Myelin Basic Protein
Corpus Callosum
Association
Astrocytes
Choroid
Aktuelle Neurologie
