Interim analysis of a non-interventional study of risperidone (RIS) treatment of psychotic and behavioural symptoms in elderly patients with dementia and vascular risk factors pre…
M Gerwe, B Ibach, J Czekalla · Aktuelle Neurologie · 2007 · Heft 09
Bibliografische Angaben
Zusammenfassung
Objectives: There is a need to safely treat psychotic and behavioural symptoms in patients with dementia and vascular risk factors. The objective of this study was to collect naturalistic data on patients who were previously unsatisfactorily pretreated with other neuroleptics. Methods: Interim analysis of a 6-week, prospective observational study (RIS-DEM-0003). Descriptive statistics used t-test and Wilcoxon-test for dependent samples. Vascular risk factors and insufficient treatment for severe chronic aggression or psychotic symptoms had to be present. Results: 336 patients (ITT; 55% with AD, 35% mixed dementi…