Neuronal plasticity in patients with Herpes simplex encephalitis: functional brain MRI studies and neuropsychological testing during the acute stage and at follow-up
C Schmidt, K Fast, N Gryschok, A Ebert, T Meindl, C Born, A Danek, HW Pfister · Aktuelle Neurologie · 2007 · Heft 09
Bibliografische Angaben
Zusammenfassung
Background: Herpes simplex virus infection of the central nervous system can manifest as potentially life- threatening necrotizing encephalitis that primarily affects the medial and inferior temporal lobe. Clinical features of acute Herpes simplex encephalitis are fever, headache, Wernicke's aphasia, epileptic seizures, confusion and reduced levels of consciousness. The affection of the temporal lobe and the limbic system may cause a significant and sometimes persisting memory impairment. However, there is evidence for a post-developmental neurogenesis in the adult human brain, especially in the temporal lobe (h…