Sentinel node biopsy performed prior to preoperative chemotherapy for axillary lymph node staging in breast cancer
P Schrenk, C Tausch, E Grafinger-Witt, T Gitter, G Hochreiner, M Fridrik, S Wölfl, S Bogner, W Wayand · Senologie - Zeitschrift für Mammadiagnostik und -therapie · 2007 · Heft 09
Bibliografische Angaben
Zusammenfassung
Sentinel node (SN) biopsy following preoperative chemotherapy (pCT) in breast cancer patients is associated with a lower identification rate (IR) and an increased false negative rate (FNR) compared to SN biopsy in patients with primary breast cancer. SN biospy was performed in 45 breast cancer patients with a clinical negative axilla prior to pCT. Following chemotherapy SN mapping was repeated and the lymph node status was assessed with axillary lymph node dissection (ALND). SN mapping prior to chemotherapy successfully identified a mean of 2.3 SNs in all patients (IR 100%). 19 patients revealed a negative SN, 2…