Antiemetics – current standards and open questions
B Pajk · Senologie - Zeitschrift für Mammadiagnostik und -therapie · 2007 · Heft 09
Bibliografische Angaben
Zusammenfassung
Chemotherapy induced nausea and vomiting (CINV) is among the most feared side effects of chemotherapy for cancer patients and is associated with significant deterioration in quality of life. The major risk factors for CINV are emetogenic potential of chemotherapeutic agents, repeated chemotherapy cycles and patient risk factors (younger age, female gender, history of motion sickness, alcohol consumption). The use of first generation 5-hydroxytryptanine (5-HT3) receptor antagonists (ondansetron, tropisetron, dolasetron and granisetron) in combination with dexamethason has significantly improved the control of acu…