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Valsalva and orthostatic maneuvers increase liver stiffness (Fibroscan®) in healthy volunteers

S Adolf, G Millonig, S Friedrich, HK Seitz, S Mueller · Zeitschrift für Gastroenterologie · 2010 · Heft 01

Dokument
1107121
CareLit-ID
Jahr
2010
Publikation
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Metadaten
DOI
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Zeitschrift
Zeitschrift für Gastroenterologie
Autor:innen
S Adolf, G Millonig, S Friedrich, HK Seitz, S Mueller
Ausgabe
Heft 01 / 2010
Seiten
–
Erschienen: 2010-01-12 00:00:00
ISSN
0044-2771
DOI
10.1055/s-0029-1246547

Zusammenfassung

Background and Objective: Liver stiffness (LS) has emerged as novel noninvasive parameter to screen for liver cirrhosis. However, other factors such as venous pressure also increase LS independent of fibrosis stage and no normal LS has been defined yet. Our aim was to study physiological conditions such as position changing and breath maneuvers on LS. Results and Methods: Measuring LS in reclined position yields the lowest and most reproducible LS of 4.7 kPa±1.3 kPa. Upright position and Valsalva maneuver independently increased LS with an enormous variability. In 20% of individuals, sitting and standing positio…

Schlagworte

Position Valsalva Increased Increase Reclined Maneuver Individuals Persons Maneuvers Liver Parameter Pressure Zeitschrift für Gastroenterologie