Treatment of chronic hepatitis c (cHC) with peginterferon alpha-2b and ribavirin in patients coinfected with HIV or HBV within a large German multicenter observational study
S Mauss, D Hüppe, M Manns, G Teuber, D Tarek, U Meyer, T Witthöft, B Möller, N Dikopoulos, J Brack, M Stern, K Dach, G Tossing, M Bilzer, E Zehnter · Zeitschrift für Gastroenterologie · 2010 · Heft 01
Bibliografische Angaben
Zusammenfassung
Aims: Treatment options for chronic hepatitis C have been continuously improved during the last decade. However subpopulations difficult to treat remain a particular challenge. Coinfection with HIV or HBV have been shown to adversely affect treatment outcome of cHC. In a large German multicenter surveillance study we assessed the effect of HIV- and HBV-coinfection on therapy compared to monoinfected pts. Methods: A total of 4061 HCV pts were treated with a combination of weight-adapted PEG-IFNα-2b and RBV. Of these, 92 (2.3%) and 73 (1.8%) had a coinfection with HBV and HIV respectively. Cirrhosis of liver was d…
