CareLit Fachartikel
Circadian gene expression in dermal fibroblasts of idiopathic hypersomnic patients and normal controls
JP Lippert, H Halfter, P Young · Klinische Neurophysiologie · 2010 · Heft 03
Dokument
1107309
CareLit-ID
Jahr
2010
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Zusammenfassung
Background: Circadian rhythm measures time on a scale of 24 hours. Many aspects of physiology show regulation within the 24 hours time slot: sleep-wake cycles and hence cognitive performance, body temperature, cardiac- (blood-pressure and heartbeat) as well as renal functions etc. On a molecular level, oscillations in the expression of specific genes evoke the alterations of the listed physiological aspects. In total, approximately 10% of all genes in mammals have circadian patterns of expression. At the core of the circadian clock mechanism is an intricate molecular mechanism driven by an interlocked network of…
Schlagworte
Blood Pressure
Dexamethasone
Biopsy
Apnoe
Blood
Lead
Klinische Neurophysiologie
