Functional Hemispherotomy: postoperative outcome and correlation to preoperative DTI

Purpose: Intractable epilepsy due to unihemispheric lesions may be treated with functional hemispherotomy (FH) to interrupt seizure propagation. Prediction of motor function after surgery is difficult: clinical presurgical workup and transcranial magnetic stimulation may remain equivocal. Our study addresses the impact of diffusion tensor tractography (DTT) on identifying prognostic parameters for motor outcome after FH. Methods and Materials: 10 patients (8m, 2 f) with pharmacoresistant epilepsy, mean age 12 (0–54) years, were evaluated with DTT prior to and post transsylvian FH. Lesions comprised six perinatal…