White matter changes in post-surgical temporal lobe epilepsy
JC Schoene-Bake, J Faber, CE Elger, B Weber · Klinische Neurophysiologie · 2008 · Heft 04
Bibliografische Angaben
Zusammenfassung
Introduction: Secondary structural damage has been reported in several studies of temporal lobe epilepsy and unilateral hippocampal sclerosis. We wanted to investigate white matter changes following temporal lobe surgery in patients with medial temporal lobe epilepsy applying diffusion tensor imaging (DTI). Methods and Subjects: We applied a novel registration and analysis approach (TBSS – Tract Based Spatial Statistics) to diffusion tensor imaging data obtained from 41 patients that underwent surgery for hippocampal sclerosis (right: n=21;left: n=20) between 1996 and 2006at our hospital and 39 age and gender ma…