Dynamic MRI and CAD vs. MRS vs. Choline PET/CT for Lesion Characterization in Prostate Cancer
M Schmuecking, H Geyer, C Boltze, KH Kloetzer, B Schilling, P Bank, TG Wendt, C Marx · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2008 · Heft 04
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Zusammenfassung
Ziele: Imaging prostate cancer with 11C-choline PET/CT a threshold SUV of 2.65 yielded an area under the receiver-operating-charcteristic (ROC) curve of 0.89 +/- 0.01 for correctly locating prostate cancer with a maximal accuracy of 84%, a sensitivity of 81% and a specificity of 87%. To evaluate the role of pre-interventional fused high resolution T2-weighted images with parametrically analyzed dynamic contrast enhanced T1-weighted MR images (DCE-MRI) and 1H MR spectroscopy (MRS) for a precise biopsy for the detection of prostate cancer and for the delineation of intraprostatic subvolumes for IMRT, findings in 6…