Emergence and transmission of second line drug resistant Mycobacterium tuberculosis complex strains in Germany
S Niemann, E Richter, S Rüsch-Gerdes · Pneumologie · 2008 · Heft 04
Bibliografische Angaben
Zusammenfassung
Aims: Drug resistant tuberculosis (TB) has become a serious challenge for global TB control. High rates of resistant and multidrug resistant (MDR, resistance to at least isoniazid and rifampin) M. tuberculosis complex (MTBC) strains have been documented in several “hot spot“ areas around the world. Additionally, increasing rates of second line drug resistance have been reported and an outbreak of an extensively resistant (XDR, defined as MDR plus resistance to any fluoroquinolone and injectable drugs) strain in South Africa has attracted world wide attention. Therefore, representative data on the prevalence and…