CareLit Fachartikel

Lipidomics in type 2 diabetic patients treated with an intestinal absorption inhibitor versus placebo: implications on metabolic learning and intestinal mucosa transdifferentiation

M Wycislo, G Liebisch, P Ugocsai, C Köhler, M Solleder, M Hanefeld, G Schmitz · Diabetologie und Stoffwechsel · 2008 · Heft 04

Dokument
1107730
CareLit-ID
Jahr
2008
Publikation
PDF
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Metadaten
DOI
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Bibliografische Angaben

Zeitschrift
Diabetologie und Stoffwechsel
Autor:innen
M Wycislo, G Liebisch, P Ugocsai, C Köhler, M Solleder, M Hanefeld, G Schmitz
Ausgabe
Heft 04 / 2008
Seiten
–
Erschienen: 2008-04-18 00:00:00
ISSN
1861-9002
DOI
10.1055/s-2008-1076197

Zusammenfassung

Electrospray ionization tandem mass spectrometry (ESI-MS/MS) allows the simultaneous analysis of a wide spectrum of lipid species (lipidomics) in plasma and other body fluids of patients to elucidate the metabolic pathophysiology of complex diseases like obesity, insulin resistance, type 2 Diabetes mellitus (T2D) or metabolic syndrome and to identify lipid biomarkers as surrogate biomarkers. Lipidomics also includes the transcriptomic analysis of the lipidome to identify the transdifferentiation of transcriptional networks involved in these diseases (metabolic learning). Recently, we have established ESI-MS/MS f…

Schlagworte

Acarbose Ceramide After Biomarkers Ceramides Diabetes Mellitus Arachidonic Acid Obesity Intestinal Mucosa Absorption Diabetologie und Stoffwechsel