CareLit Fachartikel
Impaired Insulin Secretion in Mice lacking Adenosine A1 Receptor
R Faulhaber-Walter, D Mizel, Y Huang, J Schnermann · Diabetologie und Stoffwechsel · 2008 · Heft 04
Dokument
1107733
CareLit-ID
Jahr
2008
Publikation
PDF
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Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Introduction: Adenosine has been reported to participate in maintaining glucose homeostasis. Adenosine A1 receptor (A1AR) deficient mice present with a disturbed glucose tolerance and insulin resistance. Aim of this present study was to investigate the secretory insulin function in A1AR deficient mice. Methods: Experiments were performed in male C57Bl/6 mice of the Adenosine 1A Receptor strain generated previously in our lab. Mice received standard chow. Chemicals were injected intraperitoneally. Blood was sampled by tail vein puncture. Glucose was measured by glucometer. Insulin by ELISA. Impaired glucose toler…
Schlagworte
Adenosine
After
Age Groups
Arginine
Blood
Diabetologie und Stoffwechsel
