Early clinical experience with partial amniotic carbon dioxide insufflation (PACI) during fetoscopic surgery in human fetuses

Aims: Partial amniotic carbondioxide insufflation (PACI) provides the most important strategy for improving visualization during difficult fetoscopic surgical procedures. Here we present our early clinical experience with this experimental approach in humans. Patients & Methods: Amniotic carbon dioxide insufflation was employed during a total of 29 fetoscopic procedures in human fetuses that were performed at our center between 19+2 to 33+2 weeks of gestation. Indications were twin-to-twin transfusion syndrome, diaphragmatic hernia, amnion band constriction, aortic valve stenosis, spina bifida iand laryngeal atr…