First trimester markers for pre-eclampsia: – prediction by uterine artery doppler and PAPP-A
D Lorenzi, C Scarabelli, M Rampino, L Cafaro, F Polatti · Ultraschall in der Medizin - European Journal of Ultrasound · 2008 · Heft 05
Bibliografische Angaben
Zusammenfassung
Objective: to evaluate risk of preeclampsia (PE) utilizing Doppler flussimetry of uterine arteries (FDAU) and „maternal serum pregnancy-associated plasma protein-A (PAPP-A)“ at 11–14 weeks. The sensibility/specificity (sens/spec) was estimated according to a PAPP-A cut-off level (the phase n.1); according to Doppler (phase n.2); according to integrated tests (phase n.3). Materials and methods: since 2005 we enlisted 470 physiological pregnancies for the routine ultrasonography in the first trimester. In these patients, in addiction to the normal scan, we bilaterally performed FCAU and „ultrascreen®“ (dosage βhcg…