Nonalcoholic Fatty Liver Disease progresses to HCC in the absence of apparent Cirrhosis
J Ertle, A Dechêne, JP Sowa, V Penndorf, K Herzer, G Kaiser, JF Schlaak, G Gerken, A Canbay · Zeitschrift für Gastroenterologie · 2011 · Heft 01
Bibliografische Angaben
Zusammenfassung
Background and Aims: NAFLD is the most common liver disease in developed countries, and accumulating evidence suggests it as the hepatic manifestation of the metabolic syndrome. Although the published prevalence of hepatocellular carcinoma (HCC) is low in NAFLD/NASH patients, most of these data have been derived from areas endemic for viral hepatitis. Thus we aimed to analyze a european collective of patients with a significant proportion of NAFLD associated HCC. Methods: 162 adults with HCC between 02/2007 and 03/2008 were recruited into the study. The underlying etiologies, the prevalence of the metabolic synd…