Motor-conduction failure in clinical isolated syndromes: sensitivity to detect clinically silent lesions with transcranial magnetic stimulation and the triple-stimulation technique
U. Hofstadt-van Oy, A. Weiß-Köhler, C. Klawe, D. Hagenburger, M. Strotzer, S. Lieser, P. Oschmann · Klinische Neurophysiologie · 2011 · Heft 03
Bibliografische Angaben
Zusammenfassung
Objective: To compare the sensitivity to detect motor-conduction failure in patients with „clinical isolated syndromes“ (CIS) with transcranial magnetic stimulation (TMS) and the triplestimulation technique (TST) and to describe their pathophysiology. Background: Patients with CIS like optic neuritis, myelitis, brainstem or cerebral inflammatory disease are at high risk to develop multiple sclerosis (MS). Magnetic resonance imaging (MRI) of the brain or spinal cord and neurophysiologic tests could demonstrate further lesions which are clinically silent in affected patients. TST examines the corticospinal tract b…