Metabolic and genetic predictors of circulating adipocyte fatty acid-binding protein
A Tönjes, S Kralisch, U Lößner, J Richter, P Kovacs, M Blüher, M Stumvoll, M Fasshauer · Diabetologie und Stoffwechsel · 2011 · Heft 05
Bibliografische Angaben
Zusammenfassung
Aims: Adipocyte fatty acid-binding protein (AFABP) was recently introduced as a novel adipokine playing an important role in glucose homeostasis. In the current study, we investigated the relationship between serum AFABP levels and metabolic, as well as cardiovascular parameters, in the self-contained population of Sorbs. Furthermore, we analyzed the effects of common variants in the FABP4 gene on AFABP serum concentration. Methods: Serum AFABP concentrations were quantified by ELISA and correlated with metabolic and cardiovascular parameters, as well as inflammatory markers and renal function in 868 well-charac…