3-Dimensional Structural and Volumetric Analysis of Glomeruli in Porcine Kidneys with Renal Artery Stenosis using Nano-Computed Tomography
A Brinkmann, R Moritz, E Schneck, TL Kline, DR Eaker, S von Gerlach, RM Bohle, AC Langheinrich, LO Lerman, EL Ritman · RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren · 2011 · Heft 04
Bibliografische Angaben
Zusammenfassung
Ziele: Renovascular disease is one of the most important causes of hypertension and renal dysfunction, and may lead to renal microvascular remodeling. Therefore, renal microvascular alterations were obtained in pigs after ten weeks of unilateral renal artery stenosis (RAS) using nano-CT imaging. Methode: Seven female domestic pigs (45–55kg) were implanted through PTCA with local-irritant coils in the left renal artery, provoking formation of a unilateral RAS and thus a systemic renovascular hypertension. Blood pressure was recorded using a telemetry system. The degree of RAS was determined in vivo by renal angio…
