Outcome of patients with Child-Pugh C liver cirrhosis and hepatocellular carcinoma after liver transplantation

Background: Here, we provide the first systematic outcome analysis of Child Pugh C (CPC) patients transplanted for HCC. Methods: Overall Survival (OS) of 81 CPC patients with HCC and 620 CPC patients without HCC from prospectively collected databases of 3 Austrian Transplantation centers were analyzed by uni- and multivariate analysis using the Kaplan Meier method and a Cox regression model. Results: OS was significantly shorter for CPC patients with HCC than for controls (5y OS: 49% vs. 71%, P