CareLit Fachartikel
Budesonide/ursodesoxycholic acid in sclerosing cholangitis of critical illness
M Reichmayr, K König, H Mauler, L Nitsche, W Ulrich, L Kramer · Zeitschrift für Gastroenterologie · 2011 · Heft 05
Dokument
1109388
CareLit-ID
Jahr
2011
Publikation
PDF
nein
Metadaten
DOI
ja
zitierfähig
Bibliografische Angaben
Zusammenfassung
Introduction: Recent advances in ICU care have improved survival in critically ill patients. This development has given rise to formerly unknown complications involving the biliary system. Sclerosing cholangitis in critically ill patients (SC-CIP) may develop after sepsis/shock and can rapidly progress to biliary cirrhosis. So far, ursodesoxycholic acid (UDCA) is the only recommended pharmacological therapy, but efficacy is limited. Budesonide, a topically acting oral corticosteroid with extensive first pass hepatic metabolism, could represent a potential therapeutic alternative for SC-CIP. Patients and methods:…
Schlagworte
Budesonide
After
Diagnosis
Cholangitis
Sepsis
Biopsy
Zeitschrift für Gastroenterologie
