Chronic hepatitis E in patients with CVID in Germany?
S Pischke, R Horn-Wichmann, D Ernst, BG Meyer, R Raupach, G Ahrenstorf, RE Schmidt, MP Manns, T Witte, H Wedemeyer · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Bibliografische Angaben
Zusammenfassung
Cases of chronic hepatitis E have been described in solid organ transplant recipients and HIV infected patients. In addition, Hepatitis E Virus (HEV) infections may take prolonged or chronic courses in patients with malignancies or idiopathic CD4 (+) T lymphopenia. We studied, if chronic HEV infection occur in patients with common variable immunodeficiency (CVID; n=73) in a low endemic Central European country. Of note, none of the subjects tested positive for HEV RNA or anti HEV IgG. Immunoglobulin transfusions (n=10) tested negative for HEV RNA but all were anti HEV positive. To verify that such pooled blood p…
