Chemotherapeutic use of Resveratrol on liver cancer cell lines cause damage on primary human hepatocytes
G Damm, L Hao, S Ehnert, A Blankenstein, AK Nüssler, D Knobeloch, M Glanemann · Zeitschrift für Gastroenterologie · 2012 · Heft 01
Bibliografische Angaben
Zusammenfassung
Apart from cardiac diseases, cancer is a major cause of morbidity and mortality worldwide. The resection of the tumor is a common therapeutic treatment. Alternative therapy with chemotherapeutics has often not had a selective effect on the tumor tissue and patients suffer from various side effects. Due to the limited efficiency of chemotherapy, there is growing interest in improving anticancer drugs. Resveratrol (RES), a naturally occurring polyphenol is of increasing relevance since anti-inflammatory and anti-carcinogenic properties were proven in various in vitro and in vivo studies. The anti carcinogenetic ac…