Pregnancy course and birth outcome in patients with adult onset glycogenosis type II

Aims: The obstetric risk in adult onset glycogenosis type II (Pompe disease), a skeletal muscle disease, is not known. Patients/ Methods: The pregnancy course and outcome and its effect on the muscular disorder was analysed retrospectively using a questionnaire. The women with genetically and/or biochemically confirmed Pompe disease were recruited by the German section of the International Pompe Association (n=66). The data were compared with information from the German statistical almanac, the German perinatal registry and the German registry of quality management in obstretrics. Results: 31 women responded to…