The antiarrhythmic effects of lavandulifolioside and ferulic acid from Leonurus cardiaca extracts on cardiac electrophysiology

Coronary heart disease, cardiac dysrhythmia and arterial hypertension are an important and increasing health problem in European countries. However, the application of several synthetic drugs is often limited by their adverse reactions and unwanted cardiovascular effects, especially in combination with further antiarrhythmic agents. Therefore, the research, development and use of new potential therapeutic agents of natural origin for cardiovascular diseases are essential. Recently, aqueous preparations of Leonurus cardiaca (Ph. Eur.) – such as a newly developed refined extract – were reported to exert a series o…