High response rate and improvement of long-term survival with combined treatment modalities in patients with poor-risk primary thyroid diffuse large B-cell lymphoma: an Internatio…
M Mian, G Gaidano, A Rossi, ME Cabrera, M Federico, M Martelli, H Gomez, A Lopez-Guillermo, R Tsang, E Zucca, F Cavalli, S Cortelazzo · Pneumologie · 2013 · Heft 05
Bibliografische Angaben
Zusammenfassung
Introduction: We compared clinical characteristics, prognostic factors and treatment outcome of primary thyroid DLBCL (PTL) with those of other locations of primary extranodal head and neck lymphomas (PEHNL). Methods: From December 1990 to June 2004, 48 PTL out of 478 PEHNL patients (10%) were enrolled in this study, including 10 males and 38 females, with a median age of 73 years (range, 34 – 90 years). Results: In comparison with other locations PTL cases had more frequently advanced age (> 60yrs), female sex, bulky disease, poor ECOG-PS, elevated LDH and > 1 adverse factors according to stage-modified IPI (MI…