Sensitivity of Lennard-Jones criteria in the diagnosis of Crohn's disease

Introduction: Rapid and correct diagnosis of Crohn's disease (CD) is important to impede disease progression however a gold standard is not available. Lennard-Jones et al defined macroscopic and histological criteria which are widely adopted for diagnosis of CD. Aim: To determine the sensitivity and specificity of the Lennard-Jones criteria for the diagnosis of CD. Methods: Medical records of patients with long-standing CD managed at 3 different tertiary centres (Nancy, Barcelona and Vienna) were reviewed and re-classified at time of diagnosis (up to 6 month after initial diagnosis of CD by local standards) acco…