High Prevalence of Anti-Saccharomyces Cerevisiae Antibodies in Cystic Fibrosis Patients after Lung Transplantation
K Staufer, E Halilbasic, S Harm, A Niculescu, P Jaksch, C Lichtenberger, H Vogelsang, W Klepetko, M Trauner, L Kazemi-Shirazi · Zeitschrift für Gastroenterologie · 2013 · Heft 05
Bibliografische Angaben
Zusammenfassung
Background: Autoimmune antibodies (Ab) can be found in up to 80% of CF patients prior to lung transplantation and anti-neutrophil cytoplasmic antibodies (ANCA) may be associated with severity of lung disease and disease prognosis1. In this pilot study, we investigated the prevalence of autoimmune antibodies in CF patients after lung transplantation (LuTx). Methods: Consecutive patients attending our outpatient clinic were screened for a wide range of autoantibodies in serum (ANA, AMA, SMA, EMA, TTG Ab, p-ANCA, c-ANCA, ASCA, SLA, LC-1 Ab), as well as immunoglobulins (IgG, IgA and IgM). Autoimmune diseases were ex…
