Perforation of stomach and duodenum. Unusual complications after gemcitabine treatment
J Pozsár, Á Tarpay, R Szmola, M Burai, Á Pap · Zeitschrift für Gastroenterologie · 2013 · Heft 05
Bibliografische Angaben
Zusammenfassung
Introduction: Gemcitabine is the first line treatment option of pancreatic cancer patients. This treatment modality is somewhat effective, but myriad of adverse events might ensues on the course of chemotherapy. One of the most serious side effect is systemic small-vessel vasculitis and consequent organ specific ischaemia. Renal, cutaneous and small vessel involvement of extremities are well described, but visceral manifestations are extremely rare. Our aim is to present the history of two cases with gastric and duodenal perforation as a possible consequence of gemcitabine-related vasculitis. Case 1. A 60 year o…